PDF Notes: Wbc lec 1

    Master this deck with 21 terms through effective study methods.

    Generated from uploaded pdf

    Created by @attiqzehri

    What is hematopoiesis?

    The process of blood cell formation in the bone marrow.

    What defines a lymphoid stem cell?

    It gives rise to lymphocytes, including T cells and B cells.

    What are the types of white blood cells?

    Neutrophils, lymphocytes, monocytes, eosinophils, basophils.

    How do neutrophils differ from eosinophils?

    Neutrophils respond primarily to bacterial infections, while eosinophils target parasitic infections.

    What is the normal range for neutrophils?

    40-70% of white blood cells.

    What causes leukocytosis?

    Infections, leukemia, and physiological reactions like pregnancy.

    What is neutrophilia?

    An increase in neutrophil count, often due to infections or inflammation.

    What are Dohle bodies?

    Cytoplasmic inclusions in neutrophils seen during infections.

    What is the significance of a left shift in neutrophils?

    It indicates an increase in immature neutrophils due to acute infection.

    What causes eosinophilia?

    Allergic reactions, parasitic infections, and certain hematological diseases.

    What is lymphocytosis?

    An increase in lymphocyte count, often due to viral infections.

    How does acute lymphoblastic leukemia (ALL) differ from acute myeloid leukemia (AML)?

    ALL primarily affects lymphoid cells, while AML affects myeloid cells.

    What are common symptoms of leukemia?

    Fatigue, fever, bruising, and frequent infections.

    What is the Philadelphia chromosome?

    A genetic abnormality associated with chronic myeloid leukemia.

    What is the typical age group for acute lymphoblastic leukemia?

    Most common in children, especially under 10 years old.

    What is the role of monocytes?

    They phagocytize pathogens and present antigens to T cells.

    What is the function of plasma cells?

    They produce antibodies in response to antigens.

    What is the significance of myeloblasts in acute myeloid leukemia?

    Their presence indicates a failure of normal blood cell maturation.

    What are the common causes of lymphocytopenia?

    Increased destruction, decreased production, or loss via the GI tract.

    What is the typical presentation of T-cell acute lymphoblastic leukemia?

    Often presents as a mediastinal mass in teenagers.

    What is the prognosis for acute lymphoblastic leukemia?

    Varies based on age, WBC count, and genetic factors.