Protein metabolism

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    Protein

    Created by @iibrahim

    What happens to the amino group during amino acid catabolism?

    It is removed as ammonia.

    Why is ammonia considered highly toxic?

    It is especially harmful to the nervous system.

    How is ammonia detoxified in the body?

    Converted to urea and excreted in urine.

    What is transamination?

    Exchange of amino group between an amino acid and a keto acid.

    What role do transaminases play in transamination?

    They catalyze the reaction and require pyridoxal phosphate.

    What is a key feature of the transamination reaction?

    It is readily reversible.

    What is the biological significance of transamination?

    It initiates catabolism and synthesizes non-essential amino acids.

    How are non-essential amino acids synthesized in the body?

    From keto acids through transamination.

    What does an increase in aspartate aminotransferase (AST) indicate?

    It may suggest myocardial infarction.

    What does an increase in alanine aminotransferase (ALT) indicate?

    It is associated with liver diseases.