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A pathological process resulting from severe injury leading to cell destruction.
A regulated cell death process that avoids inflammation.
Necrosis is uncontrolled and causes inflammation, while apoptosis is controlled and does not.
Lack of oxygen, toxins, burns, and severe physical damage.
Cell membrane rupture and release of cellular contents.
Cells activate enzymes to degrade their own DNA and proteins.
Decreased ATP production leading to cell death.
They signal inflammation and tissue damage to the immune system.
It serves as a biomarker for heart muscle damage.
Increased eosinophilia and loss of normal structure.
DNA damage and accumulation of misfolded proteins.
Activation of harmful enzymes leading to cell injury.
They cause oxidative damage to lipids, proteins, and DNA.
Irreversible mitochondrial dysfunction and severe membrane damage.
Preservation of tissue architecture despite cell death.
Transformation of tissue into a viscous liquid due to cell digestion.
Tuberculosis infections leading to cheese-like necrotic tissue.
Release of pancreatic lipases leading to fat destruction.
It manages protein folding; stress leads to apoptosis if overwhelmed.
They assist in proper protein folding and prevent misfolding.
Cells degrade their own components to survive nutrient deprivation.