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A serious infection affecting the meninges in the brain or spinal cord.
Bacterial meningitis typically presents with cloudy cerebrospinal fluid and elevated white blood cell counts.
The presence of elevated granulocytes indicates infection.
A gram-negative diplococcus responsible for epidemic meningitis.
Polysaccharide capsule, endotoxin, and opacity proteins enhance its pathogenicity.
It helps resist phagocytosis and serves as an antigen in vaccines.
LOS acts as an endotoxin that triggers severe inflammatory responses.
Petechial bleeding, high fever, and shock are typical symptoms.
A life-threatening condition caused by meningococcemia leading to adrenal hemorrhage.
Fever, headache, stiff neck, and increased PMNs in cerebrospinal fluid.
Deficiencies in complement components C6–C9 raise susceptibility.