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Study of how the body affects a drug.
Process by which a drug enters the bloodstream.
How a drug spreads through the body's tissues.
Chemical alteration of a drug in the body.
Removal of a drug from the body.
Oral is safer but absorption is variable.
Fraction of administered drug reaching systemic circulation.
pH, blood flow, surface area, and contact time.
Affects ionization and solubility of drugs.
Indicates how extensively a drug disperses in the body.
First-order is concentration-dependent; zero-order is constant rate.
Enzyme system involved in drug metabolism.
Ratio of toxic dose to effective dose of a drug.
Decreased response to a drug after repeated use.
A drug that activates a receptor.
A drug that blocks receptor activation.
Full agonists produce maximum response; partial do not.
Measures the body's ability to eliminate a drug.
Limits the free concentration of the drug in tissues.
To quickly achieve therapeutic drug levels.
Restricts drug access to the central nervous system.
Competitive bind to the same site; non-competitive bind elsewhere.