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A bacterial zoonosis primarily from infected ruminants and swine.
Strains of the Brucella genus, particularly B. melitensis.
Brucellosis has an undulating fever pattern and musculoskeletal symptoms.
Sheep, goats, and camels.
Varies from 1 week to several months.
Fever, sweats, fatigue, and musculoskeletal pain.
Through ingestion, inhalation, or direct contact with infected animals.
They are key target cells for Brucella, allowing persistent infection.
It aids in resistance to phagocytosis and plays a role in pyrogenicity.
Blood cultures, serologic tests, and PCR.
Combination therapy with doxycycline and rifampin or streptomycin.
Endocarditis, affecting the aortic valve.
Increased incidence of fetal loss, but not teratogenic.
Vaccination of animals and pasteurization of milk products.
Relapse occurs in up to 30% of poorly compliant patients.
Brucellosis shows noncaseating granulomas without acid-fast bacilli.