A&P Lecture

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    What is the role of ATP in muscle contraction?

    ATP provides the energy required for muscle contraction by enabling the myosin heads to detach from actin filaments and re-cock for the next power stroke. It is essential for the cross-bridge cycle in skeletal muscle fibers.

    Describe the steps involved in excitation-contraction coupling.

    Excitation-contraction coupling involves three main steps: 1) Neural control through the generation of an action potential in the sarcolemma, 2) Excitation where the action potential travels along the sarcolemma and down the T-tubules, and 3) Calcium ion release from the sarcoplasmic reticulum, which initiates muscle contraction.

    What factors determine the peak tension developed during a muscle contraction?

    Peak tension in a muscle contraction is determined by the frequency of stimulation, the number of motor units recruited, the initial length of the muscle fibers, and the type of muscle fibers involved.

    How does the motor unit contribute to muscle tension production?

    A motor unit consists of a motor neuron and the muscle fibers it innervates. The recruitment of multiple motor units increases the overall muscle tension produced, allowing for graded responses to varying levels of force required.

    Compare isotonic and isometric muscle contractions.

    Isotonic contractions involve a change in muscle length while generating tension, such as lifting an object (concentric) or lowering it (eccentric). Isometric contractions occur when muscle tension is generated without a change in length, such as holding a weight steady.

    What are the physiological factors responsible for muscle fatigue?

    Muscle fatigue is primarily caused by a decrease in pH due to lactic acid accumulation, depletion of energy reserves (ATP and glycogen), and alterations in ion concentrations affecting muscle excitability and contraction efficiency.

    What processes do muscle fibers use to obtain energy for contractions?

    Muscle fibers obtain energy through three main processes: aerobic metabolism (using oxygen), anaerobic glycolysis (producing ATP without oxygen), and the breakdown of creatine phosphate for quick energy bursts.

    When do muscle fibers produce lactate, and what is its significance?

    Muscle fibers produce lactate during anaerobic glycolysis when oxygen supply is insufficient, typically during intense exercise. Lactate can be used as an energy source or converted back to glucose in the liver.

    What is the significance of muscle tone in skeletal muscles?

    Muscle tone refers to the continuous and passive partial contraction of muscles, which helps maintain posture and readiness for action. It also contributes to increased resting metabolism due to energy consumption by activated muscle fibers.

    How do different types of muscle fibers relate to muscle performance?

    Different muscle fiber types (slow-twitch vs. fast-twitch) influence muscle performance. Slow-twitch fibers are more efficient for endurance activities, while fast-twitch fibers are suited for short bursts of power and speed.

    What is the recovery period in muscle physiology?

    The recovery period is the time required for muscle fibers to return to pre-exertion conditions after fatigue. This can take several hours to a week, depending on the intensity of the exercise and the individual's fitness level.

    What is the difference between concentric and eccentric contractions?

    Concentric contractions occur when a muscle shortens while generating force, such as lifting a weight. Eccentric contractions occur when a muscle lengthens while still generating force, such as lowering a weight.

    What are the basic reactants that mitochondria absorb to synthesize ATP?

    Mitochondria absorb oxygen and substrates such as glucose and fatty acids from the cytosol to synthesize ATP through aerobic metabolism.

    Define a motor unit and its role in muscle contraction.

    A motor unit is defined as a single motor neuron and all the muscle fibers it innervates. It plays a crucial role in muscle contraction by coordinating the activation of muscle fibers to produce force.

    How does the number of fibers in a motor unit affect precision in body movements?

    The number of fibers in a motor unit affects precision; smaller motor units allow for finer control and precision in movements (e.g., eye muscles), while larger motor units are used for gross movements requiring more force (e.g., leg muscles).